Production and marketing growth price fluctuate vitamin E prospects remain positive

Writer:医药经济报Source:医药经济报 Date:2017-07-22

  In recent years, China's vitamin E (VE) production and export volume have been increasing, but the market price fluctuation, and the amplitude is larger, attracting attention.

  Production relative concentration 

  VE is divided into natural products and finished products, with natural VE production accounting for only about 20%. Over the years, the United States has been a major producer of the world's synthetic VE, producing about 40 percent of the world's total output, and other large state-owned Germany, Switzerland, Japan, France and so on. At present, the world VE production capacity is about 140,000 tons, and the production giants have the company of DSM, basf and so on. Our country has become the largest VE production country in the world, with annual production capacity of more than 100,000 tons and annual output of more than 70,000 tons. 

  As of June 20, 2017, there are 375 national vitamin E production approval Numbers. Among them, the API production approval number 7, the main production enterprise of Zhejiang pharmaceutical co., Ltd. Xinchang pharmaceutical factory, chongqing southwest synthetic pharmaceutical co., Ltd., Zhejiang NHU Company Ltd., wuxi fu qi pharmaceutical co., Ltd., shaanxi west pharmaceutical co., Ltd., etc. 

  VE's synthesis process needs more than 20 steps, and the reaction step is much, the process line is long, the technical requirement is high, its production equipment is mostly specialized equipment, the technical barrier is higher. Therefore, for a long time, only a handful of global production of VE, there are mainly the Netherlands, DSM, Germany basf and zhejiang medicine in our country, the new synthesis and so on four big enterprise, the company's production capacity combined accounted for about 90% of the world, form a pattern of oligopoly. 

  Among them, the Netherlands, DSM (annual production capacity of 25000 tons) and Germany's basf (20000 tons) accounted for about 50% of capacity, zhejiang pharmaceutical (22000 tons, is China's largest, the world's second largest producer) and the new and into (15000 tons) accounted for about 40% of capacity. These four enterprises are based on the basic raw materials, such as m-cresol, which has a strong technical barrier. Over the years, China has produced VE API in addition to new and zhejiang medicine, as well as southwest synthesis. Recently, some enterprises have entered the production line of synthetic VE

  According to CFDA website statistics, as of the end of June 2017, a number of enterprises in China have obtained the 26 GMP certification of VE. Among them, the majority of enterprises with GMP certificate are: zhejiang new and cheng shares (4), zhejiang pharmaceutical xinchang pharmaceutical factory (3), southwest synthetic pharmaceutical (3); Zhejiang pharmaceutical vitamin factory, roche (Shanghai) vitamin company, Peking University medicine, zhejiang jinliyuan pharmaceutical, shaanxi xiyue pharmaceutical obtained 2; Zhejiang jutai pharmaceutical co., anhui big Oriental pharmaceutical co., LTD., zhejiang nojin pharmaceutical co., LTD., northeast pharmaceutical general plant, zhejiang anglikang pharmaceutical co., ltd. and huazhong pharmaceutical co., LTD. 

Fluctuation of price 


  In recent years, China's VE export growth has been strong, accounting for 80% ~ 90% of the world trade volume, and the main export destinations are North America, Western Europe and Asia. Over the years, the United States has been the largest exporter of VE in China, exporting over 10,000 tons, accounting for more than a quarter of the total exports. Germany is also a big exporter to China, with an export volume of over 10,000 tons, accounting for nearly a quarter.


  In recent years, international market VE price fluctuation, and the amplitude is larger. Average export prices in 2015 were only 46 per cent of 2011, not even half of that. In those days, the market price of VE in China also fell. In early January 2015, the average price of the domestic feed grade VE (50%) was 6,3100 RMB per ton. In October 2015, it was 43,520 yuan; By the end of December, the average price of the manufacturer was RMB 41,000 per ton, down 35.36%, and some dealers sold only RMB 39,000 per ton. Because VE market price keeps falling, China's production enterprises are generally in difficulty.


  In 2016, VE market price started to stabilize and recover. VE had a strong price rise at the end of February 2016. In mid-april 2016, domestic market VE price reached 5,9600 yuan per ton, up 44% from the beginning of the year. In this year, international market VE prices are also rising, and the price of VE prices of our exports has been rising, from us $8 per kilo in 2015 to about us $14 per kilogram.


  VE export prices have risen sharply, the manufacturers are profitable and companies have been running full capacity. Other companies saw this huge profit and added to the production line. VE produced a quick increase in production, and the market supply and demand balance was broken. In 2017, VE's market price began to decline. In the middle of June 2017, the price of the feed grade VE in China is low, and some manufacturers are quoted at RMB 4000 per ton. 

Outlook remains positive 

  According to the analysis, the market demand of VE will continue to grow in the future, and the prospects are promising. There are three main reasons:


  The first is that the market should be widely used. Since 1977, the Chinese pharmacopoeia has been collected by the Chinese pharmacopoeia. In addition, it has been paid to us pharmacopoeia USP40, UK pharmacopoeia BP2017, Japanese pharmacopoeia JP17, Korean pharmacopoeia 10th edition and EP9.0 of European pharmacopoeia. VE is an early into the varieties of over-the-counter drugs in our country, according to the CFDA website relevant statistical data show that as of June 20, 2017, the national over-the-counter medicines involving VE there are 61, both single preparations, there are also many compound preparations.


  VE is also a variety of vitamins, such as 21 gold, he, good deposit, golden scherkang products. These products have entered thousands of households, with annual sales of tens of billions of yuan and are expected to continue to rise in China, with a population of 1.3 billion (including more than 200 million elderly people).


  In the beauty respect, VE to skin's beauty maintenance effect is certain, foreign major washing company's high and middle grade skincare beauty products all use VE as an important additive. In recent years, more and more home-made washing companies have also launched VE's skin-care products to the market, which has great potential.


  Second, there is progress in clinical research. In recent years, domestic and foreign experts and scholars on the physiological and pharmacological effects of VE conducted in-depth research, found that the various metabolic processes involved in the body of VE, broad and complex, have many similar to ginseng effect, clinical value more and more important, use very much, have been involved inside and outside, women, son, the division such as infection, skin, radiation, become one of the popular modern drugs.


  Third, the demand for feed additives is large. At present, about 80% of the world's VE is used as feed additives, such as the appropriate amount of VE in the feed of egg chicken per kg, which is 5 international units. Twenty percent of VE is used in medicine and food. The VE is mainly used for feed additives, basf and DSM mainly produce the high-end pharmaceutical food grade VE. As the global population continues to increase, the world economy gradually rise, feed production growth significantly, the current annual output has reached 1 billion tons, the global feed the future global feed production is expected to maintain the steady growth of around 2%, the future VE demand is also rising.


  The development of China's breeding industry has led to a significant increase in the production of various feeds. According to rough statistics, nearly 10 years, the average annual increase about 8 million tons of feed, now more than 4000 national about mixed feed production, annual production of feed about 200 million tonnes a year, about 1/5 of the world. Along with our country people's living standards continue to improve, the breeding will develop steadily in the coming years, by 2020, China's feed annual output will reach 240 million tons, accounting for about a quarter of the global total, feed additives will growing demand for VE





TypeInfo: Industry news

Keywords for the information:China's vitamin E (VE) production and export volume are increasing